منابع مشابه
cer and the Complement Cascade
ownload pite significant research on the role of inflammation and immunosurveillance in the immunologic nvironment of tumors, little attention has been given to the oncogenic capabilities of the complement e. The recent finding that complement may contribute to tumor growth suggests an insidious relationship n complement and cancer, especially in light of evidence that complement facilitates ce...
متن کاملOsteoarthritis and the Complement Cascade
Accumulating evidence demonstrates that complement activation is involved in the pathogenesis of osteoarthritis (OA). However, the intimate complement regulation and cross talk with other signaling pathways in joint-associated tissues remain incompletely understood. Recent insights are summarized and discussed here, to put together a more comprehensive picture of complement involvement in OA pa...
متن کاملCancer and the complement cascade.
Despite significant research on the role of inflammation and immunosurveillance in the immunologic microenvironment of tumors, little attention has been given to the oncogenic capabilities of the complement cascade. The recent finding that complement may contribute to tumor growth suggests an insidious relationship between complement and cancer, especially in light of evidence that complement f...
متن کاملComplement receptor is an inhibitor of the complement cascade
A glycoprotein from the membrane of human erythrocytes has been identified as a receptor for C3b (CR1). It promotes the dissociation of the alternative pathway C3 convertase C3b,Bb and the cleavage of C3b by C3b/C4b inactivator. We find that CR1 also inactivates the C3 and C5 convertases of the classical pathway. CR1 inhibits the consumption of C3 by C3 convertase EAC142 and enhances the decay ...
متن کاملPlatelets and the complement cascade in atherosclerosis
Atherosclerosis and its late sequels are still the number one cause of death in western societies. Platelets are a driving force not only during the genesis of atherosclerosis, but especially in its late stages, as evidenced by complications such as arterial thrombosis, myocardial infarction, and ischemic stroke. Atherosclerosis is increasingly recognized as an inflammatory disease, influenced ...
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ژورنال
عنوان ژورنال: MedEdPORTAL
سال: 2012
ISSN: 2374-8265
DOI: 10.15766/mep_2374-8265.9070